Psychiatria pre prax 4/2024
Prechod na LAI aripiprazol (dvoj-injekčný štart) u pacienta s hebefrénnou schizofréniou
Predkladám kazuistiku 20-ročného muža s diagnózou hebefrénna schizofrénia, ktorý bol od svojich 17-tich rokov psychiatricky periodicky hospitalizovaný vo viacerých zariadeniach pre opakované relapsy prevažne afektívnej a negatívnej symptomatiky. Pacienta sa dlhodobo nepodarilo stabilizovať pomocou vhodnej antipsychotickej medikácie, nakoľko nikdy neboli symptómy dostatočne zaliečené a mali dosah na celkové fungovanie pacienta v bežnom živote. Pacient prešiel do starostlivosti našej ambulancie, po snahe upraviť medikáciu sa stav opäť dekompenzoval a bola nutná hospitalizácia na našej klinike. U pacienta sme inicializovali antipsychotickú liečbu aripiprazolom s prechodom na LAI formu v kombinácii s olanzapínom a tymostabilizátorom. Podarilo sa nám stav pacienta stabilizovať a dosiahli sme sociálnu úzdravu s redukciou porúch správania.
Kľúčové slová: psychóza, hebefrénna schizofrénia, kombinovaná antipsychotická liečba, aripiprazol, LAI
Transition to LAI aripiprazol (dual-injection start) in a patient with hebephrenic schizophrenia
I am presenting a case study of a 20-year-old man diagnosed with hebephrenic schizophrenia. Since the age of 17, he has been repeatedly hospitalized in various psychiatric facilities due to recurrent relapses, primarily of affective and negative symptoms. For a long time, we were unable to find a suitable antipsychotic medication for the patient, as his symptoms were never adequately controlled and had a significant impact on his daily life. The patient was referred to our outpatient clinic. Despite attempts to adjust his medication, his condition decompensated again, necessitating hospitalization at our clinic. We decided to treat the patient with aripiprazol and transition to a long-acting injectable (LAI) form, combined with olanzapine and a mood stabilizer. We were able to stabilize the patient‘s condition and achieve social recovery.
Keywords: psychosis, hebephrenic schizophrenia, combined antipsychotic therapy, aripiprazole, LAI
