Via practica 7-8/2009

Arterial thromboprophylaxis in medical and angiological practice

Antiplatelet therapy by acetylsalicylic acid (aspirin) provided pivotal advances in the prevention and treatment of obliterating (coronary; cerebral, extremities, renal, genital, ocular and other peripheral) arterial cardio-vascular diseases. Currently available antiplatelet drugs have some limitations which might be overcamed by improved dosing regimens, use of combination of agents affecting different platelet functions and, in particular, by the new antiplatelet drugs with distinct pharmacodynamic properties offering new advantages, including faster onset of action, greater potency, and reversibility of effects.

Keywords: arterial vascular system, arterial thrombosis, arterial thromboprophylaxis, classical antiplatelet drugs, new antiplatelet agents