Vaskulárna medicína 1/2014

Sledování účinku antiagregační terapie v sekundární prevenci ischemické cévní mozkové příhody

Antiplatelet therapy for secondary prevention in patients with mainly vascular non-cardioembolic strokes is essential. Aware of the risk of side effects especially the combination of antiplatelet drugs, adverse interactions with other medications and possible resistance to various antiplatelet agents, we are obliged to choose not only an individual approach, but also selected antiplatelet therapy monitored with both clinical and laboratory. In our study, we investigated a group of 79 (58 males) patients after ischemic stroke or transient ischemic attack who were hospitalized in the Neurology department of the hospital in Trebic in 2008–2011. In terms of work, we chose initially after the accident antiaggregation acetylsalicylic acid at a dose of 100 or 200 mg ASA. Patients were monitored for clinical and laboratory at regular intervals for 12 months. During the monitoring was necessary to adjust the medication in a total of 7 patients.

Keywords: stroke, monitoring, antiplatelet therapy.