Vaskulárna medicína 2/2013

Bleeding thrombocytopathies

Bleeding thrombocytopathies are congenital and acquired diseases caused by disorders of platelet function at multiple levels. The pathogenesis is therefore highly variable in this group of diseases with a clinical manifestation especially by bleeding signs of various intensity. In the article we deal with the possibilities of diagnosis, differential diagnosis and current methods used in the treatment of bleeding thrombocytopathies. We have focused mainly on the hereditary qualitative platelet disorders, because despite of their rare occurrence they can cause even the lifethreatening bleeding and therefore it is necessary to take them into account in the differential diagnosis of other bleeding states.

Keywords: bleeding thrombocytopathies, differential diagnosis, treatment.