Vaskulárna medicína 2/2020

Fibromuscular dysplasia

Fibromuscular dysplasia is an idiopathic, segmental disease of the muscular layer of the arterial wall leading to stenosis of the small and medium arteries. The diagnosis is based on a typical angiographic finding, according to which we distinguish between focal and multifocal type. The phenotype includes not only stenosis but also dissection, aneurysm and tortuosity of the arteries. It occurs mainly in women, most often affecting the renal and cerebrovascular arteries, but fibromuscular dysplasia has been described in almost all arteries, including coronary arteries. It is often a multi-vascular disability. The article analyzes the main symptoms, diagnosis, classification, differential diagnosis and current view on the management of various types of this disease according to the current SVM/ESH consensus on fibromuscular dysplasia from 2019.

Keywords: fibromuscular dysplasia, focal, multifocal stenosis