Urologie pro praxi 3/2021

Peyronie's disease – today's treatment options

Peyronie's disease, or plastic penile induration (IPP), is a very unpleasant disease that causes patients a lot of hardship and is far from rare. It often occurs in older men with the typical age of onset of difficulty 50–60, but it also occurs in younger men. The aetiology is not exactly known, but a local autoimmune disease is assumed. The article discusses risk factors, the course and treatment of the disease. The treatment is divided into conservative, with intra – and surgical treatments having the most promising results. Intralesional therapy may reduce the indication of surgery or change the technique to be performed, but only after full instruction by the patient. The decision on the most appropriate surgery to correct penile curvature is based on pre-operative evaluation of penile length, degree of curvature and status of erectile dysfunction (ED). If there is concomitant ED that does not respond to pharmacological treatment, implantation of a penile prosthesis, with or without straightening the penis, is the best option.

Keywords: Peyronie's disease, plastic penile induration, penile deviation, penile angulation, erectile disfunction.