Urologie pro praxi 3/2024

Metabolic risk factors or renal cell carcinoma

Renal cell carcinoma is common in developed countries in Europe and North America. These regions are characterized by high income and the so-called „western“ lifestyle which is associated with the occurrence of metabolic syndrome and its components. These have an impact not only on cardiovascular disease and diabetes, but also on the development of malignant tumours. Obesity and hypertension are typical risk factors for renal cell carcinoma. This review describes the relationship between known metabolic risk factors and renal cancer carcinogenesis, while also discussing possible preventive strategies to improve metabolic dysfunction and thus reduce the risk of (not only) renal cell carcinoma.

Keywords: diabetes, metabolic syndrome, obesity, renal cell carcinoma, risk factors.