Urologie pro praxi 3/2020

Prostate rebiopsy: when should be performed?

Prostate rebiopsy is indicated in case of the permanently elevated or increasing level of prostate specific antigen (PSA). Other indications include low free to total PSA ratio or high Prostate Health Index (phi). Histological parameters for the indication of rebiopsy include atypical small acinar proliferation (ASAP), high-grade prostatic intraepithelial neoplasia (HG-PIN) in more than two biopsy cores specimens, small atypical glands associated with HG-PIN (PINATYP) or intraductal carcinoma. Multi-parametric magnetic resonance imaging is used mainly in the repeat prostate biopsy because it can more often detect significant prostate cancer compared to standard biopsy.

Keywords: prostate rebiopsy, atypical small acinar proliferation, high-grade prostatic intraepithelial neoplasia, multi-parametric magnetic resonance imaging of the prostate.