Psychiatria pre prax 4/2002
PITFALLS OF POLYPHARMACOTHERAPY
The present paper supplies basic information about the pharmacological risks of polypharmacotherapy in psychiatry. The positive features and the drawbacks of combined therapy are discussed and the possible mechanisms of drug interactions on the pharmacokinetic and pharmacodynamic levels are described.
Keywords: polypharmacotherapy, psychotropic drugs, drug interactions, pharmacokinetics, pharmacodynamics.