Psychiatria pre prax 5–6/2010
Intracranial bleeding associated with selective serotonin reuptake inhibitor paroxetine and coadministration with ibuprofen
The observational case report deal with a 48-year old woman who used paroxetine and ibuprofen developed intracranial bleeding. Paroxetine and ibuprofen synergistically inhibit platelet function. Doctors should be aware of the increased risk of hemorrhage among patients on selective serotonin reuptake inhibitors.
Keywords: paroxetine, ibuprofen, antiplatelet activity, intracranial bleeding.
