Psychiatria pre prax 6/2007

HOW TO PREDICT THE RESPONSE TO ANTIDEPRESSANTS?

Evidence based medicine confirmed that antidepressants are effective in the treatment of depression, but until today it is not clear what antidepressant would be best for which patient. Results from EEG studies indicate that after one week of antidepressant treatment we can correctly predict 8 out of 10 patients will not responsed to treatment with a given antidepressant if we continue with it further 3–7 weeks. EEG could help to chooise right antidepressant in similar way as cultivation helps to choose right antibiotic.

Keywords: antidepressants, prediction, electroencephalography, depressive disorder