Pediatria pre prax 1/2008

PROBIOTICS, PREBIOTICS AND ATOPY

The extreme prevalence of atopic diseases in developed countries is related to altered colonization of the intestines with commensal microbiota as well as to failure of the mucosal immune system to develop into a tolerogenic, non-inflammatory status. Probiotics and prebiotics may be able to improve this aberrant condition. They represent a complimentary therapeutic approach and particularly the unique opportunity of primary prevention in high-risk subjects.

Keywords: probiotics, prebiotics, intestinal microflora, mucosal immune system, atopic diseases.