Neurológia pre prax 2/2009

Stereotactic lesional surgery in treating pharmacoresistant epilepsy

Despite advances in imaging techniques and electrophysiological diagnosis in patients with pharmacoresistant epilepsy, there remain a significant proportion of patients in whom a resection procedure is not feasible or is associated with severe adverse effects. Such patients are potential candidates for stereotactic surgical intervention. The paper reviews the history and current situation of stereotactic lesional interventions used in the treatment of pharmacoresistant epilepsy, their options and results. Stereotactic surgical technique has become the basis of other techniques relevant to epilepsy surgery, namely radiosurgery and neuronavigation.

Keywords: pharmacoresistant epilepsy, stereotactic lesionectomy, radiosurgery.