-1.png)
Neurológia pre prax 1/2009
Classic form of Huntington’s disease manifested by asymmetric Parkinson’s syndrome with rigidity responding to levodopa
Huntington’s disease is a hereditary neurodegenerative disease primarily affecting striatal neurons, manifested mostly in adulthood by a combination of neurological and psychiatric symptoms, most typically by choreatic hyperkinesias and development of dementia. We report a case of a female patient with Huntington’s disease presenting as multisystem atrophy (MSA) with delayed manifestation of chorea. Unlike a typical MSA presentation, asymmetry in manifestations of Parkinson’s syndrome and responsiveness to levodopa were evident.
Keywords: Huntington’s disease, Parkinson’s syndrome, „MSA-like” form, rigidity, levodopa.
