Neurológia pre prax 2/2013

Epilepsy in patients with multiple sclerosis

Epilepsy and multiple sclerosis (MS) are disorders often seen in daily clinical praxis by neurologists. Rarely they occur together. Then question about their pathophysiological relation logically arises. New knowledge about the pathophysiology of these two disorders and progress of neuroimaging methods should be helpful in clarifying the relationship between these two disorders. According to several epidemiological studies, which analyzed the incidence and risk of epilepsy in patients with MS, the incidence of seizures is higher in patients with MS and seizures are caused by cortical and subcortical lesions and by their accompanying oedema. In this article authors conclude current knowledge of coincidence of both diseases.

Keywords: epilepsy, multiple sclerosis, cortical lesions, antiepileptic therapy.