Neurológia pre prax 1/2013
Chlamydophila pneumoniae and multiple sclerosis
Chlamydophila pneumoniae is an intracellular pathogen and important cause of respiratory tract infection. Monocytes may traffic Chlamydophila pneumoniae across the blood-brain-barrier but there is a strong evidence that Chlamydophila pneumoniae has not causal role in multiple sclerosis. Chlamydiae are susceptible to antibiotics that afect DNA and protein synthesis, including macrolides, azalide, specifically azithromycin, tetracyklines, and chinolones. Long-term antibiotic treatment of chronic disaeses, such as multiple sclerosis, Alzheimer´s disease, asthma, atherosclerosis, is unlikely show any benefit.
Keywords: chlamydiae, Chlamydophila pneumoniae, Chlamydophila pneumoniae and multiple sclerosis, chlamydiae and chronic sequalae, treatment.
