Dermatológia pre prax 1/2008
UREA – ALWAYS ACTUAL AND DISCUSSED
Urea (carbamidum) is a substance used for a long time in dermatology and cosmetic products in various formulas and concentrations. That causes variabilities in the assessment of pharmacological and clinical effect. An important biological role of urea in the phylogenetic progress of barrier functions in vertebratea (in amphibians) and in the consolidating of optimal hydration and barrier function of the skin surface in human is presented in this report. Results of this work imply topics for further clinical possibilities of the utilization of urea and for scientific research concerning urea both in pharmacology and dermatology.
Keywords: urea, zevní terapie.
