Via practica 3/2005

CURRENT VIEW OF PATHOGENESIS AND THERAPY OF ACNE

The pathogenesis of acne is complex, with strong evidence supporting the involvement of sebaceous hyperplasia, follicular hyperkeratinisation, bacterial hypercolonisation and inflammation. The improved understanding of the pathogenetic mechanisms of acne has brought about changes in acne management. It is becomig clear that combination therapy should be utilized as early as possible, preferably at the initiation of therapy, to simultaneously attack two or three pathogenic factors.

Keywords: acne vulgaris, pathomechanisms, therapy