Via practica 2/2007

May probiotics influnce negative outcomes of antibiotic therapy to normal flora?

Normal flora contains anaerobic and facultative anaerobic bacterias. Antibiotic use is the most common factor, which leads to destruction and reduction of physiologic normal flora. Antibiotics affects everywhere in site of penetration to all susceptible bacterias. Use of antibiotics is associated with colonization of pathogenic bacterias and other pathogenic microorganizmus and especially with diarrhea. Use of probiotics which contains S. boulardii, L. acidophilus, B. breve, Streptococcus salivarius a Enterococcus fecalis leads to decreasing diarrhea incidence in about 54 % and decreasing of travel diarrhea incidence in 34 %. effect of probiotics is more expressed in children than in adults.

Keywords: normal flora, antibiotics, diarrhea, probiotics.