Via practica 5/2009

Classification of dyslipoproteinaemias: Part I – Primary dyslipoproteinaemias

Classification of dyslipoproteinaemias (DLP) takes through long development. Recently most extended classification is the one established by European Atherosclerosis Society in 1992. It is based on the examination of total cholesterol and triglyceride levels. From this point of view we can divide DLP into isolated hypercholesterolaemia, combined hyperlipoproteinaemia and isolated hypertriglycerideaemia. From etiology point of view we identify primary DLP (genetic basis) and secondary DLP (coexist with other diseases, which cause alteration in metabolism of lipids and lipoproteins). The most important from primary DLP (we touch this topic on first part of article) are familial hypercholesterolaemia, familial defective apo B100, polygenic hypercholesterolaemia, familial combined hyperlipoproteinaemia, familial hyperchylomicronaemia, polygenic familial hypertriglycerideaemia and familial dysbetalipoproteinaemia.

Keywords: dyslipoproteinaemias, classification of dyslipoproteinaemias, primary dyslipoproteinaemias.