Via practica 12/2008

DIFFUSE LARGE B-CELL LYMPHOMA

Diffuse large B-cell lymphoma is the most frequent form of non-Hodgkin‘s lymphoma and can be diagnosed either in a local or in diffuse form. The initial evaluation of a patient with suspected lymphoma must establish the precise histological subtype, the extent and sites of disease and the performance status of the patient. The diagnosis, treatment, and prognosis of DLBCL are strongly dependent upon obtaining this information. DLBCL is potentially curable, aggressive lymphoproliferative disease. Treatment consists of chemo immunotherapy with or without radiation therapy. Following the completion of therapy patients should be followed longitudinally for relapse and later to monitor chronic and late treatment complications.

Keywords: DLBCL, symptoms, diagnostics, treatment, toxicity