Vaskulárna medicína 1/2017

National registry of thrombophilic states in Slovak Republic

Thrombosis or thromboembolic disease is a state associated with the development of blood clot (thrombus) in the vascular system. According to the Wirchov´s triad, except the damage to the vessel wall and slowing of the blood flow, changes in the contents of blood including inherited and acquired prothrombotic disorders of haemostasis also influence its development. Thrombophilia is the state characterized by the increased tendency to form the intravascular arterial or venous thrombus. According to the concept of healthcare in the field of Haematology and Transfusiology, published in the Journal of Ministry of Health of the Slovak Republic (special issue, 31.8.2006, volume 54), besides the complex care of patients with disorders of haemostasis, the role of the National Centre of Haemostasis and Thrombosis (NCHT) with the seat at the Department of Haematology and Transfusiology of the Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and Martin University Hospital, in the maintenance of the National Registry of Thrombophilic States of the Slovak Republic (NRTS SR) is declared. This unique registry collects data of individuals with thrombophilia, provided by the experts from regional haematologic outpatient departments with consent of the patient once a year in the special simple forms. After their registration in the electronic system, the data are available for the statistical analysis and assessment of particular characteristics of the patients. Therefore, in this article we report the cross-sectional analysis performed during the annual processing of data of the individuals with thrombophilic state. We would also like to point out to the significance of the diagnostics of thrombophilia for further management of the affected patients and briefly characterize the risk that they convey.

Keywords: thrombophilia, thrombosis, risk factor, predisposition