Vaskulárna medicína 1/2017

Clinical pathophysiology, diagnostics and pharmacological treatment of chronic venous disease

Chronic venous disease (CVD) belong to the most common diseases in developed countries. The disease pathophysiology is complex and involves genetic susceptibility and environmental risk factors. The fundamental basis for CVD development is inflammation within the venous circulation (the venous walls, valves and microcirculation) that is subjected to increased venous pressure. Patients with CVD develop varicose veins, swelling, skin changes and are at risk of venous ulceration. The quality of life of patients suffering from chronic venous disease is decreased in comparison with healthy population. Early diagnostic and proper treatment is therefore essential. In this article the clinical pathophysiology, diagnostic and pharmacological treatment of chronic venous disease is discussed.

Keywords: chronic venous disease, pathophysiology, diagnostic, pharmacological treatment