Vaskulárna medicína 2/2014

Pharmacotherapy of chronic venous disorder

Chronic venous disorder (CVD) is a common illness with high incidence existing especially in Europe and North America. The main goal of Venoactive Drugs (VAD) is to eliminate the symptoms of CVD (venous pain, fatigue, etc.). But there are some VAD that could be used also for treatment of venous oedema and venous ulcer. There are many papers that prove their effectiveness in the experiment and in the microcirculation. The most effective substance is micronized purified flavonoid fraction (MPFF) of diosmin hesperidin. It is proved that this substance could be used as an effective supplementary treatment of symptoms after venous intervention. Only MPFF diosmin hesperidin received the best recommendation – 1B in the last guidelines for VAD therapy.

Keywords: chronic venous disorder, venoactive drugs, micronized purified flavonoid fraction of diosmin hesperidin.