Urologie pro praxi 5/2018

Vitamin D3, its aspect and possible use for urology

There is increasing evidence from experimental and epidemiological studies suggesting that vitamin D deficiency may be the cause of increased morbidity, cancer and associated mortality. The vitamin D deficit is very widespread and most of the population in Europe, especially in the northern part, suffers from a deficiency. Promising knowledge about vitamin D3 in prevention and treatment has been known for over 30 years. Significant results with D3 supplementation were achieved for colorectal cancer and breast cancer. The thesis deals with the effects of vitamin D3 on prostate cancer. The results are controversial. Recommended doses in various studies include a safety margin of 600 to 4000 IU per day, but according to several authors the recommended dose is at least 4000–5000 IU. Lower levels do not reach the sufficient level and the desired beneficial effect.

Keywords: vitamin D, sufficient dose, prostate cancer.