Urologie pro praxi 3/2016

Mixed tumour of a solitary kidney

Malignant tumours of the renal parenchyma account for 1%–2% of all malignant tumours in adults. Carcinoma is the most common tumour. Most carcinomas are sporadic, with only about 4% being familial. Mixed tumours are rare and, in the case of their occurrence, one must bear in mind that these can be so-called hereditary carcinomas.

Keywords: mixed tumour, hereditary carcinoma, Knudson hypothesis, Birt-Hogg-Dubé syndrome, folliculin, genetic examination.