Urologie pro praxi 1/2018

Uncomplicated lower urinary tract infections in women – options of treatment and prevention

Urinary tract infections (UTIs) are among very frequent medical conditions for which women visit their general practitioner. Acute uncomplicated cystitis the diagnosis of which is usually straightforward is the most common manifestation of UTIs in women. When choosing an appropriate antimicrobial agent, it is advisable to take into consideration its pharmacokinetics, the assumed spectrum of efficacy, and the effect on the vaginal flora. Short-term treatment with a duration of three to five days is preferred. In women with recurrent cystitides, following the commencement of appropriate therapy and retreatment of infection, it is necessary to perform a comprehensive urological evaluation in order to rule out functional or anatomical abnormalities. This almost invariably involves urine culture and targeted retreatment according to susceptibility. The review article presents differentiated options of treatment and prevention of lower urinary tract infections in women with both antimicrobial agents and lifestyle measures plus preparations not included in the group of antimicrobial agents; however, when indicated correctly, their administration can bring long-term relief to these women.

Keywords: acute uncomplicated cystitis, recurrent cystitis, complicated urinary tract infection, asymptomatic bacteriuria.