Urologie pro praxi 3/2024

Drug interactions in urology in patients with hypertension

Drugs commonly used in urological daily practice have a high potential for pharmacodynamic and pharmacokinetic drug interactions. In patients treated for hypertension, the choice of molecule must be carefully considered within the individual indications in order to minimize adverse effects (hypertension or postural hypotension). Similarly, in patients treated for lower urinary tract symptoms, choose antihypertensives that will not primarily lead to worsening of their symptoms. The article summarizes clinically significant drug interactions between antihypertensives and drugs used to treat overactive bladder, benign prostatic hyperplasia, and antiandrogen interactions.

Keywords: arterial hypertension, drug interactions, muscarinic receptor antagonists, beta-3-agonist, alpha-1-blockers, androgen antagonists.