Urologie pro praxi 4/2024

Ambulatory parenteral antibiotic therapy in urology: innovations and perspectives

The review article addresses the issues of outpatient parenteral antibiotic therapy (OPAT) in urology. OPAT is a treatment modality that allows intravenous administration of antibiotics in an outpatient setting. Urology is one of the fields where OPAT can be utilized, most commonly to treat urinary tract infections caused by multidrug-resistant bacteria (e. g., ESBL-producing strains) in patients whose health condition does not require hospitalization. OPAT can be implemented in several ways: administering long-acting antibiotics (ceftriaxone, ertapenem, gentamicin, and amikacin) once daily at the clinic or the application of various antibiotics continuously using an elastomeric pump. Abroad, it is also common to provide OPAT at home, most often by home care nurses or even by trained patients or their relatives.

Keywords: OPAT, antibiotics, urinary tract infections, outpatient therapy, multidrug- -resistant bacteria.