Psychiatria pre prax 4/2017

Mirtazapine in clinical practice

Mirtazapine belongs to antidepressants with a dual mechanism of action (NaSSAs), influencing serotonergic and noradrenergic neurotransmission. It is an antidepressant with a high efficacy in the treatment of depression. The efficacy of mirtazapine is comparable with or higher than that of other antidepressants. It is different in the onset of action and in the profile of adverse events. The aim of this article is to provide more information about this antidepressant and describe the type of patients who are suitable for this medication.

Keywords: mirtazapine, depression, meta-analysis, efficacy, sleep, sexual dysfunction