Psychiatria pre prax 4/2011

The effect of antidepressants on serum lipid parameters

The disorder of lipid metabolism is part of the metabolic syndrome and systemic metabolic disorders, which affects the individual are mutually conditional, but the exact cascade formation is not yet clear. Effect of antidepressants and the pathophysiology of depression in lipid metabolism are not well enough understood. In our work we had to determine the effect of different types of antidepressants (SNRIs and SSRIs) to change the values of lipid profile – triglycerides, LDL and HDL.

Keywords: SNRIs, SSRIs, depression, triglycerides, LDL, HDL.