Psychiatria pre prax 1/2006

CURRENT TRENDS IN THE BIOLOGICAL TREATMENT OF ALZHEIMER DISEASE

We do not knot complex etiology of Alzheimer disease so far. That is why we are not able to treat such a sever dementia causally. Procedures that affect known pathogenetic chains are used. Evidence based management is only a treatment with acetylcholineesterase inhibitors and memantin. Some other procedures are reported, but their effect is not positively confirmed as with procedures mentioned above.

Keywords: Alzheimer disease, dementia, acetylcholineesterase inhibitors, cognitive function, memantin, nerve growth factors, nootropics, free oxygen radicals scavengers.