Psychiatria pre prax 4/2017

Rational use of psychotropic drugs in oncology – selected indications, interactions, tips for practice

Indications psychotropic drugs in oncology include also chemotherapy-induced neuropathy, delirium, nausea, emesis and affect appetite. Psychotropic drugs are often used “off label” and should be used in patients to attention. Levels of some of psychotropic drugs may be affected by a number of concomitantly administered drugs due to pharmacokinetic drug interactions. Dexamethasone, phenytoin, and carbamazepine are often the co-medication with the above-mentioned indications, among the important enzyme inducers and may reduce the effect of psychotropic drugs. Combinations of psychotropics potentially increased risk of pharmacodynamic drug interactions.

Keywords: psychotropic drugs, onkology, drug interaction