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Psychiatria pre prax 2/2015
Pregabalin therapy in generalized anxiety disorder and alprazolam dependence
Prescription drug misuse and abuse are also common problems in primary care settings. Substances of abuse have profound effects on neurotransmitter systems involved in the pathophysiology of anxiety disorders and, with chronic use, may unmask a vulnerability or lead to organic changes that manifest as an anxiety disorder. Generalized anxiety disorder (GAD) follows a chronic period with low rates of remission and frequent relapses. Comorbid substance use disorder decreases the likelihood of recovery from GAD and increases the risk of exacerbation.
Keywords: pregabalin, anxiety, generalized anxiety disorder, drug dependence.
