Psychiatria pre prax 1/2001

New registrated antipsychotics

During last 2 years 4 atypical neuroleptics have been registered: quetiapine, amisulprid, ziprasidon, zotepine. In a brief review their pharmacological profile, pharmacodynamic and pharmacokinetic properties, clinical studies and side effects are given. These neuroleptics render us more choices of available drugs, but only clinical practice will prove their advantage or disadvantage for our patients.

Keywords: atypical neuroleptics, quetiapine, amisulprid, ziprasidon, zotepine.