Psychiatria pre prax 5/2005

PHARMACOTHERAPEUTIC OPTIONS IN DEPRESSION

The importance of antidepressants for the further development of psychiatry is summarized. In more details 2 groups of antidepressants, e.g. specific antidepressant influencing preferentially serotonin or norepinephrine/dopamine and dual antidepressants are discussed. New indication within depressive disorder – targeted treatment of depression according to prevalence of symptoms, residual symptoms and breakthrough of pharmacoresistance are discussed. Because the specific antidepressants are well tolerated and safe, the indications are widened also outside the range of depressive disorders.

Keywords: specific antidepressants, dual acting antidepressants, target symptoms, residual symptoms, breakthrough of pharmacoresistance, indication.