Psychiatria pre prax 5/2008

INDIVIDUALIZED TREATMENT IN THE LIGHT OF CURRENT GUIDELINES

The paper deals with possibilities of individualized treatment within individual steps of actual Czech guidelines for treatment of depressive disorder. Giving the first choice includes all available antidepressants (AD), it is necessary to tailor the choice to the clinical picture and individual tolerability. At the level of the second step the strategies of AD change, dose escalation and augmentation are discussed in more details. The further strategies include combinations of antidepressants and other less common treatment options.

Keywords: guideline for treatment, depressive disorder, psychopharmacotherapy, antidepressants, individualized treatment