Psychiatria pre prax 2/2020

Iatrogenic, drug‑ induced depressions

Pharmacologically induced depressions represent complications of patients’ health and worsen their prognoses. A big range of drugs has a depressogenic potential: antiparkinsonian drugs (L-dopa, amantadine), anticonvulsants (topiramate, phenobarbital), disease-modifying drugs used for multiple sclerosis (interferon-α, glatiramer acetate), drugs used in oncology (interleukins, procarbazine, vincristine), antihypertensive drugs (methyldopa), corticoids, benzodiazepines, opioid analgesics (pethidine), antibiotics (ciprofloxacin), antiviral drugs etc. This review summarizes the most common drug-induced depressions and possibilities of their solutions.

Keywords: drug‑induced depresssion, adverse drug effects