Psychiatria pre prax 5/2008

PHARMACOLOGICALLY INDUCED DEPRESSION

Pharmacologically induced depression is often underestimated in clinical practice. It is caused usually by treatment of somatic disease. There are a number of known effective substances with properties to induce secondary depressive symptoms as a part of their adverse reactions. The author in this article points out major drug groups that have the potential to trigger drug induced depression. The article does not have the ambition to be completely comprehensive ant it is not possible also because of the topic character. The goal of the article is to draw psychiatrists attention to this problem who serve as consultants for nonpsychiatry departments and also attention of other colleagues taking care of psychiatry patients with somatic diseases.

Keywords: depression, adverse drug reaction, somatic disease and its treatment