Psychiatria pre prax 1/2019

Drug induced movement disorders – basics for pharmacologists

Drug induced movement disorders may appear after number of pharmacological treatments. Dopaminergic-treatment related chorea in Parkinson’s disease and tardive dyskinesia are the ones most well described. Determination of the type of hyperkinesia is very important for the diagnosis of drug-induced movement disorders, as the treatments differ across the various clinical phenomena. Treatments are based on tapering of dose or discontinuation of offending drug but may include also targeted pharmacotherapy, botulinum toxin or deep brain stimulation.

Keywords: akathisia, dystonia, tardive dyskinesia, drug-induced parkinsonism, neuroleptic malignant syndrome