Psychiatria pre prax 1/2004

Demention with Lewy’s Bodies, Diagnosis, Clinical Meaning, Treatment

Lewy’s Bodies Demention (DLB) is the neurodegenerative disease between Parkinson’s and Alzheimer disease. DLB has got common signs and special signs – mostly hallucination humans and animals, and changing levels of cognition and sensitivity to neuroleptics. The prevalence of DLB si rather high, specialy at the old age about 10–20 % of all type of demention. The clinical diagnosis is just about 4 %. DLB is often mistaken with Alzheimer Disease, clinical manifestation is not conspicuous. Diagnosis meaning is treatment decision – neuroleptics are not first choice medicine. Cholinesterasis inhibitors is better choice or carefull taking a new antipsychotics with low level potention to make Parkinson syndrome.

Keywords: demention with Lewy’s Bodies (LBD), Lewy Body Disease (LBD), Parkinson’s Disease, nontypical antipsychotics, classical neuroleptics, cholinesterasis inhibitors.