Psychiatria pre prax 2/2012
Circadian rhythms and depression
There is an evidence for the link betweeen circadian rhythms dysfunction and pathophysiology of depression. Manipulation of the circadian timing system via sleep deprivation, light therapy, or antidepressant agomelatine with new mode of action may represent inovative style of treatment in major depression.
Keywords: circadian rhythms, major depression, phototherapie, sleep deprivation, lithium, fluoxetine, agomelatine.
