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Psychiatria pre prax 3/2006
ATYPICAL ANTIPSYCHOTICS IN TREATMENT RESISTANT DEPRESSION
Clinical trials indicate that approximately 50 % of depressed patients have had an inadequate response to antidepressant therapy. Poor response to adequate antidepressant treatment according treatment guidelines has been termed as treatment resistant depression (TRD). Recent data indicate that atypical antipsychotics can serve as adjunctive as well as alternative agents in the treatment of drug-resistant depressive disorder.
Keywords: treatment resistant depression, atypical antipsychotics.
