Praktické lekárnictvo 3/2016

N-acetylcysteine in current clinical praxis

N-acetylcysteine belongs to commonly used drugs from expectorants. Its mechanism of action is not based on the modified mucus formation and/or its structure in airways only, however, it possesses also antioxidant and immunomodulatory properties. These activities are discussed here in the context of its current therapeutic use with a special focus on paediatric population.

Keywords: expectorants, cough, N-acetylcysteine, NAC, cystic fibrosis