Praktické lekárnictvo 1/2017

Generics and their therapeutic position, the risk of substitution in pharmacies

Therapeutic position of generics is frequently discussed. Physicians of various fields often question whether they are as effective and safe for their patients as the original drug. The aim of the article is to summarize the problematics, from the development to the practical impact on disease management in accordance with current knowledge, with an explanation of some ambiguities.

Keywords: generic, brand, bioequivalence, efficacy, safety