Praktické lekárnictvo 4/2017

Cilostazol in treating lower limb ischaemia

Cilostazol is a vasodilator with antiplatelet and metabolic properties.In addition to physical activity, it is used in the treatment of intermittent claudications, i.e.classic clinical signs of chronic limb ischaemia.Professional societies’ guidelines list it as the first drug of choice.While the effect of cilostazol on claudications has been evaluated in a number of studies, its options for affecting the individual cardiovascular and cerebrovascular risks still remain unappreciated.

Keywords: antiaggregation, thrombocytes, vasodilation, intermittent claudications, critical limb ischaemia, stroke prevention