Pediatria pre prax 6/2012

Current status of treatment of growth disorders

An examination of a child with growth disorder must always be complex. Current indications to the growth hormone therapy are: growth hormone deficiency in children, growth hormone deficiency in adults (severe deficiency of growth hormone), Turner syndrome, growth failure in children with chronic renal failure, growth failure in children with intrauterine growth retardation (IUGR/SGA, intrauterine growth retardation/small for gestational age), Prader-Willi syndrome, deficiency of SHOX gene (e.g. Leri-Weill syndrome). In other cases of growth disorder we have to exclude primary cause (e.g. therapy of hypothyroidism, diet in coeliac disease).

Keywords: short stature, growth disorder, growth hormone therapy.