Pediatria pre prax 2/2015

Histiocytoses

Histiocytoses are hematologic diseases that can be benign as well as life-threatening disorder. It is necessary to consider these diseases despite of their rare incidence. Present classification considers patogenesis of these disorders that is useful to predict prognosis and planning therapy. This article is concerned on the most common clinical histiocytic disorders which is Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis.

Keywords: histiocytoses, macrophages, dendritic cells, Langerhans cell histiocytosis, hemophagocytic lymphohistiocytosis.