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Pediatria pre prax 3/2007
ANTIHISTAMINES IN PEDIATRIC CLINICAL PRACTICE
Antihistamines are among the most widely prescribed drugs worldwide. They are nearly irreplaceable in the treatment of allergy. Since the discovery of antihistamines substantial progress has been made in understanding the molecular mechanisms of action. Concurrently new therapeutic indications have opened and new adverse effects have been identified. Second generation antihistamines are considered far much safer and effective, about which we have hundreds of well documented clinical and pharmacological data.
Keywords: histamine, antihistamines, anti-inflammatory activity, clinical indications, adverse effects.
