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Pediatria pre prax S1/2012
Current data about HPV vaccination
Prophylactic vaccination against human papillomaviruses is intended for primary prevention of cervical cancers. Currently, there are two approved vaccines – bivalent vaccine Cervarix, which protects against HPV 16, 18 and due to cross-protection against HPV 31, 33, 45 and quadrivalent vaccine Silgard, which protects against HPV 6, 11, 16, 18 and against HPV 31 due to cross-protection. Clinical trials showed high efficacy and safety of both vaccines. Mass vaccination of HPV „naive“ persons could prevent most of the cases of cervical cancers and benign condylomas.
Keywords: HPV, cervical carcinoma, precancer lesion, vaccination.
